insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web

Caution should be taken in people with kidney disease, insulin resistance, type 2 diabetes, obesity, heart disease, and in children.1213 Dosage Always speak with a healthcare provider before taking a supplement to ensure that the supplement and dosage are appropriate for your individual needs. —Elizabeth Barnes, Verywell Health, 26 Nov. 2024

Low levels of magnesium may also worsen insulin resistance, which can increase the risk of developing type 2 diabetes.15 One study found that adding 100 milligrams of magnesium per day to your diet decreases the risk of diabetes by 15%. —Soma Mandal, Health, 2 Dec. 2024

Eventually, this can damage your liver, promote insulin resistance, and increase your risk of more severe liver conditions. 6. —Lauren Panoff, Mph, Rd, Verywell Health, 2 Dec. 2024

In the United States, 38.4 million people have diabetes, and 95% are Type 2 caused by insulin resistance. Worse, and waiting in the wings, are 97.6 million people over the age of 18 who have prediabetes. —Bryant Stamford, The Courier-Journal, 7 Nov. 2024

Word History

First Known Use

1927, in the meaning defined above

Medical Definition

insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes